Immunotherapy with Allergen Peptides

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Immunotherapy with Allergen Peptides

: Specific allergen immunotherapy (SIT) is disease-modifying and efficacious. However, the use of whole allergen preparations is associated with frequent allergic adverse events during treatment. Many novel approaches are being designed to reduce the allergenicity of immunotherapy preparations whilst maintaining immunogenicity. One approach is the use of short synthetic peptides which represent...

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Allergen Peptides, Recombinant Allergens and Hypoallergens for Allergen-Specific Immunotherapy

Allergic diseases are among the most common health issues worldwide. Specific immunotherapy has remained the only disease-modifying treatment, but it is not effective in all patients and may cause side effects. Over the last 25 years, allergen molecules from most prevalent allergen sources have been isolated and produced as recombinant proteins. Not only are these molecules useful in improved a...

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Recent Progress in Allergen Immunotherapy

The efficacy of allergen immunotherapy for the treatment of allergic rhinoconjunctivitis with or without seasonal bronchial asthma and anaphylaxis caused by the sting of the hymenoptera class of insects has been clearly demonstrated in numerous well-designed, placebo-controlled trials. Immunotherapy whether by subcutaneous injection of allergen extract or by oral/sublingual routes modifies peri...

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Allergen immunotherapy

Allergen Immunotherapy (AIT), is effective in reducing the clinical symptoms associated with allergic rhinitis, asthma and venom induced anaphylaxis [1]. Subcutaneous (SCIT) and Sublingual (SLIT) with unmodified allergen extracts are the two routes of administration of allergen vaccines. In addition, AIT has been positioned as the only treatment that may alter the natural course of allergic dis...

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Patient’s compliance with allergen immunotherapy

BACKGROUND Allergen immunotherapy (IT) is an effective treatment of respiratory allergy, but requires strict rules of performance. This makes compliance particularly relevant, but thus far only a few studies have investigated this issue. METHODS We reviewed all the available articles on compliance and adherence with IT in its different forms of administration, ie, subcutaneous (SCIT), subling...

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ژورنال

عنوان ژورنال: Allergy, Asthma, and Clinical Immunology

سال: 2007

ISSN: 1710-1484

DOI: 10.2310/7480.2007.00004